Kluber was removed from Tuesday night's game at Detroit after three innings because of back discomfort. He will face the Tigers in the third game of a four-game series on Wednesday. The 30-year-old Venezuelan sustained his second loss in his last three trips to the mound on Friday as he was taken deep twice in a 3-1 setback to Seattle to increase his home run allowed total to five.
Cody Allen walked two in the ninth but struck out Jim Adduci with the tying run on third to end it. Allen has seven saves in seven chances.
"Right out of the gate, he had a really good slider", Indians manager Terry Francona said.
"My first time in the big leagues didn't go this way and a year ago I had one at-bat, so to get up here and be able to help and produce is a great feeling".
Ramirez gave the Indians a 2-0 lead with his big hit in the fourth, and he scored on a sacrifice fly by Jason Kipnis.
Detroit Tigers starting pitcher Justin Verlander throws during the first inning of the team's baseball game against the Cleveland Indians, Tuesday, May 2, 2017, in Detroit.
Cabrera said the Tigers were being cautious on his first day back from the injury but he seemed optimistic he would be able to play on Wednesday.
Cabrera was activated after missing the minimum of 10 days with a strained right groin.
Cabrera was batting.268 (15-for-56) with two doubles, three home runs and nine RBIs in 16 games before going on the DL.
Left-hander Gio Gonzalez drove in Washington's other run with a third-inning groundout. Sanchez hit 20 homers in 53 games as a rookie last season. Bauer threw a season-low 54 percent (50-of-93) of his pitches for strikes. The over/under total for the game is set at 7.5 runs.
Diamondbacks 6, Nationals 3 • Jake Lamb and Chris Herrmann homered off Tanner Roark, and visiting Arizona bounced back from an early deficit to beat high-scoring Washington.
On a 1-2 pitch from Bauer, Collins belted a three-run home run to right field, and his second round-tripper of the season gave the Tigers a 5-0 edge over the Indians.
Ausmus was asked before the game about giving Jose Iglesias a day off in favor of Romine, who started at short.
Kluber is 3-2 with a 5.06 ERA in six starts this season. On a cold, damp night, he left for a defensive replacement after seven innings.