"I think the heart, mind and attitude of the horse are big factors in the recovery", Breen told CNN.
"It means a lot", Velazquez said of winning with Pletcher, the trainer he has teamed with so successfully over the years.
The winning horse entered the race as the favorite at 9-2.
"And like we talked about it, I felt like for the first 25 starters I had to defend my Derby record".
Lookin At Lee was one of three horses Asmussen saddled in this year's Derby.
LOUISVILLE, Ky. (AP) - Already well connected in the business world, Anthony Bonomo hooked up with trainer Todd Pletcher to prepare an entry for the Kentucky Derby. "I think it will be a quiet environment and give him time to settle in and if we need to make any adjustments we'll have time to do that". What's he doing with more last-place finishes than first-place finishes in the Derby?
The pressure was on the New York-based Pletcher, whose Derby record of one victor from 45 previous runners was much talked about prior to the race on Sunday morning (AEST). "It felt like I really needed that second one".
Velazquez was able to break well from the gates and used his colts speed to tuck in behind State of Honor's bullet run after several other horses were bumped or boxed in.
Always Dreaming returned $11.40, $7.20 and $5.80 for a $2 bet.
"Physically, he's fine. So as long as (his eye) continues to get better, we plan on being at Pimlico".
Classic Empire was the original choice coming off a win in the Breeders' Cup Juvenile, but he delivered a clunker in his first race of the year and then missed five weeks of training because he was injured, refused to train or both. The track is impossible.
Gunnevera, who finished seventh following a rough trip, is a possibility, pending a meeting between trainer Antonio Sano and the Fountain of Youth winner's owners.
On the final turn, Always Dreaming took command as State of Honor faded.
Always Dreaming, who looked "super" yesterday morning, is scheduled to be shipped directly to Pimlico early tomorrow morning. "On the turn I asked him and he didn't really respond, but then he surprised me and kept on after the victor", said Prat. "I thought at the quarter pole, I hadn't really asked him that much yet", said Lanerie. "He did it himself from there".
"I got a great ride", trainer Ian Wilkes said.
Turns out the dark brown colt knew best.
The morning began very cold with track conditions rated sloppy as horses slogged through the mud.
"I think it's even more special than the first one", he said, per NBC Sports.
It was Always Dreaming's his fourth straight victory, proving his five-length win in the Florida Derby was no fluke.
The swarm's picks for second and third-McCracken and Irish War Cry-finished eighth and tenth, respectively.
The victory was worth $1,635,800.
Always Dreaming's primary ownership is comprised of Bonomo's Brooklyn Boyz Stables and Teresa Viola, whose husband Vincent owns the NHL's Florida Panthers. Pletcher also trains Tapwrit and Patch, the one-eyed-colt that was a sentimental favourite, but lost the race coming in at 14th place.
Thunder Snow did not finish the race. "He broke well out of the gate and got a good position". He was caught by the outrider and walked back to the barn on his own. The Derby's ultimate victor, Always Dreaming, was ranked fourth by the predictive system, with only a 65% chance to finish in the top four.
Trainer Todd Pletcher won the Kentucky Derby for the second time. Nothing against all the others, but this was the best horse.
"I don't know what happened at the start", Thunder Snow's rider Christophe Soumillon said of his horse's early trouble.
A total of 147 horses ran in the 14 races on Saturday, down from 155 horses on the Derby Day card previous year. William Hill US reopened Always Dreaming at 13-4 odds to win the Triple Crown.
That allowed some generous-priced horses to hit the ticket.
The Always Dreaming - Lookin at Lee exacta was worth $336.20 for a $2 wager. Lookin at Lee paid $20.20 and $15.20.