Trump has given US military commanders broader discretion to order strikes than his predecessor, former President Barack Obama.
Adam Stump, a Pentagon spokesman, said the bomb was dropped from a U.S. MC-130 special operations transport. It was developed during the second Iraq war but never used.
The GBU-43 is created to destroy surface and underground bunkers, mainly by collapsing them and sucking the oxygen out. Other types of bombs can be more effective against deeper, hardened tunnels. Congresswoman Barbara Lee said the unprecedented use of a MOAB, which is considered the 'Mother of All Bombs, ' marks a new front in the nearly 16 year war in Afghanistan.
Trump described the bombing as a "very successful mission". The military is now analyzing the Bomb Damage Assessment (BDA).
However, the strike has provoked a mixed reaction from people around the world, with some arguing the strike is accordance with Trump's election promises while other arguing it wasn't.
The Afghan government was aware of the U.S. plan to bomb the IS tunnel complex, presidential spokesman Shah Hussain Murtazawi suggested. "So, what I do is I authorize our military", Trump said when asked whether he authorized the strike.
Now, it's important to note that back in 2001, the US used something similar on several occasions.
So far, Trump has offered little clarity about a broader strategy for Afghanistan, where some 8,400 US troops remain.
"The United States takes the fight against ISIS very seriously and in order to defeat the group, we must deny them operational space, which we did", Spicer said, using an acronym for Islamic State.
"At 7:32 p.m. local time today, U.S. Forces - Afghanistan conducted a strike on an ISIS-K tunnel complex in Achin district, Nangarhar province, Afghanistan, as part of ongoing efforts to defeat ISIS-K in Afghanistan in 2017", U.S. Forces - Afghanistan said in a statement Thursday.
Economically speaking, Business Insider reported that USA stock prices dropped slightly across the board after the announcement of the bombing, though officials said it will take more time to see the long-term impact of the attack.
The Pentagon said in its statement that "U.S. Forces took every precaution to avoid civilian casualties with this strike".
The Taliban, the insurgent group that has fought the United States and the Afghan government since 2001, also clashes with the Islamic State, though many of its members have defected to the terrorist group.
The bombing in Afghanistan comes a week after Trump authorized a United States missile strike against a Syrian government air base - the first USA strike against the Syrian government in the country's six-year civil war.
It is the first time the bomb, called a GBU-43, has ever been used in combat. We know that it's very big - 27,100 pounds or so - and works well against caves and tunnels.
"North Korea is a problem - the problem will be taken care of".
Afghan forces and the American troops advising them have engaged in heavy fighting with ISIS forces in Afghanistan over the past year. The authority to deploy the weapon was granted to Nicholson by the commander of U.S. Central Command, General Joseph Votel.
USA officials say intelligence suggests Islamic State is based overwhelmingly in Nangarhar and neighboring Kunar province.