The Scannell brothers and Andrew Conway could win their first Ireland caps in the Six Nations against either Scotland or Italy.
Niall and Rory Scannell, along with Munster team-mate Andrew Conway have been called up to their first Ireland Six Nations squad.
It means a total of 13 Munster players are included.
Ireland head coach Schmidt said: "It has been good to watch the players over the past two months and great to see many of them doing so well".
Ireland faces Scotland in Edinburgh on February 4 and then plays Italy in Rome the following weekend.
"As always there were some hard decisions but we feel that the group is a good mix with a number of key players having good experience and a number of newer players having gained valuable experience and confidence during the summer tour to South Africa and the recent Guinness Series".
Forwards: Finlay Bealham (Connacht), Rory Best (Ulster), Jack Conan (Connacht), Ultan Dillane (Connacht), Tadhg Furlong (Leinster), Cian Healy (Leinster), Jamie Heaslip (Leinster), Iain Henderson (Ulster), Billy Holland (Munster), Dave Kilcoyne (Munster), Dan Leavy (Leinster), Jack McGrath (Leinster), Sean O'Brien (Leinster), Tommy O'Donnell (Munster), Peter O'Mahony (Munster), Donnacha Ryan (Munster), John Ryan (Munster), Niall Scannell (Munster), CJ Stander (Munster), Devin Toner (Leinster), James Tracy (Leinster), Josh van der Flier (Leinster).